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Prediabetes and the Truth 

Diabetes does not develop overnight; rather it unfolds over an extended period of time. As the body gradually encounters problems that impair its ability to regulate blood glucose levels, this gradual deterioration eventually results in a permanent increase in blood glucose.  Remarkably, during much of this progression, most individuals won't manifest any noticeable symptoms. If we overlook the disease and neglect early intervention, our body's primary defense mechanism will adapt silently, albeit at the cost of sustaining damage. This continues until diabetes becomes irreversible. 

Traditional Blood Glucose Testing Cannot Prevent Diabetes 

How can you discover your condition and improve before it worsens to diabetes? 

Relying on a generic blood glucose test alone is not enough. In the early phases of the disease, as the pancreas begins to produce less insulin and insulin sensitivity diminishes, the body strives to maintain blood glucose within the normal range. If the abnormal blood glucose level is detected only after insulin secretion has dropped by 50%, it may already be too late. While blood glucose testing is valuable for diagnosis, it cannot prevent diabetes.

As the condition progresses, blood glucose may initially rise slightly while still remaining below the diabetic threshold, a stage commonly known as prediabetes. According to research findings, individuals with prediabetes face an increased risk of cardiovascular disease, cancer, kidney disease and death that is 1.5 to 2 times higher than that of people with normal blood glucose. Meanwhile, younger prediabetes (20-39 years old) have a 50% chance – and are 22 times more at risk than older prediabetes (80 years old and above)¹ – of developing diabetes. It goes without saying that whether it evolves in diabetes or not, prediabetes can have a detrimental impact on the body. 

Currently, the most reliable test for diagnosing prediabetes is the Oral Glucose Tolerance Test (OGTT), which is superior to both the fasting blood glucose (FBG) and the Glycated Hemoglobin (HbA1c) due to its significantly higher sensitivity² (the sensitivity of FBG and HbA1c is only 25% and 49% of OGTT). However, the testing process of OGTT is relatively more complicated. After giving a fasting blood sample, a patient must drink a 75-gram glucose solution within 5 minutes before waiting two hours to take another blood test.


DForesee® is suitable for people without diabetes, in which combines your genetic and health data to calculate your risk of developing diabetes. Personalized reports are accompanied by comprehensive health advice to help prevent diabetes and protect your health.

Click here to learn more about the DForesee® test.

​For further information or inquiries about our diabetes tests, please click the button on the bottom right to send us a WhatsApp message.


  1. International Diabetes Federation. IDF Diabetes Atlas, 10th edn. Brussels, Belgium: 2021. Available at:

  2. Salehidoost R, Mansouri A, Amini M, Aminorroaya Yamini S, Aminorroaya A. Diabetes and all-cause mortality, a 18-year follow-up study. Sci Rep. 2020 Feb 21;10(1):3183. doi: 10.1038/s41598-020-60142-y. PMID: 32081921; PMCID: PMC7035261. 

  3. 衞生署衞生防護中心生命統計數字 

  4. Zhang X, Wu H, Fan B, Shi M, Lau ESH, Yang A, Chow E, Kong APS, Chan JCN, Ma RCW, Luk AOY. The role of age on the risk relationship between prediabetes and major morbidities and mortality: Analysis of the Hong Kong diabetes surveillance database of 2 million Chinese adults. Lancet Reg Health West Pac. 2022 Sep 22;30:100599. doi: 10.1016/j.lanwpc.2022.100599. PMID: 36419741; PMCID: PMC9677132. 

  5. Barry E, Roberts S, Oke J, Vijayaraghavan S, Normansell R, Greenhalgh T. Efficacy and effectiveness of screen and treat policies in prevention of type 2 diabetes: systematic review and meta-analysis of screening tests and interventions. BMJ. 2017 Jan 4;356:i6538. doi: 10.1136/bmj.i6538. PMID: 28052845. 

  6. Li G, Zhang P, Wang J, An Y, Gong Q, Gregg EW, Yang W, Zhang B, Shuai Y, Hong J, Engelgau MM, Li H, Roglic G, Hu Y, Bennett PH. Cardiovascular mortality, all-cause mortality, and diabetes incidence after lifestyle intervention for people with impaired glucose tolerance in the Da Qing Diabetes Prevention Study: a 23-year follow-up study. Lancet Diabetes Endocrinol. 2014 Jun;2(6):474-80. doi: 10.1016/S2213-8587(14)70057-9. Epub 2014 Apr 3. PMID: 24731674. 

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